Resveratrol
Grape -
A Natural Cancer Fighting Compound?
More
than a decade ago, resveratrol was discovered as a component of
red grape skins that acted as a natural antidote to cancer.
Resveratrol, a plant antibiotic, is released by several species of
plants in response to pathogenic invasions, and has been speculated as
the cause of the French Paradox. Despite having a diet high in
saturated fats, southern European nations such as France and Italy
demonstrate a significantly lower incidence of coronary heart disease.
Scientists have related this phenomenon to the moderate concentration
of resveratrol in red wine, which acts both as an anti-cancer agent
and an anti-inflammatory agent.
What
is Resveratrol Grape?
But what
exactly is resveratrol, and how does it function? Resveratrol
is a phytoalexin, or plant antibiotic, that is found in particular
abundance in the skins of muscadine grapes. In fact, muscadine wines
contain five times the normal amount of resveratrol than regular red
wines. In purified form, the compound is a white powder with a slight
yellow tinge. Studies conducted by a group of researchers working for
Nature Journal in 2003 showed that resveratrol's ability to counteract
the detrimental effects of a high-fat diet was based on its opposition
of the alteration of the 144 and 155 gene pathways changed by a high-
fat diet. Scientists hope that this discovery will be able to remedy
the increasingly high-fat diet that is plaguing the American
population.
Resveratrol
Grape
Extract - A natural cancer fighting compound?
More
significant work has
been done to identify the oncological
benefits of resveratrol. A report on the work appears in the July 2000
issue of Cancer Research, where it is explained that trans-
resveratrol, or Res, turns off NF-kappa B, a protein that prevents
cancer cells from being killed by the body. The benefits of resveratrol
are evident and clear in small rodents and invertebrates. Perhaps in
the future, research can be done to identify the real potential
benefits resveratrol may have for human beings.
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